SYSTEMATIC OPTIMIZATION OF CAPILLARY ELECTROPHORETIC SEPARATIONS

Electrophoretic separations on microfluidic chips.

This review presents a brief outline and novel developments of electrophoretic separation in microfluidic chips. Distinct characteristics of microchip electrophoresis (MCE) are discussed first, in which sample injection plug, joule heat, channel turn, surface adsorption and modification are introduced, and some successful strategies and recognized conclusions are also included. Important achiev...

Nanomaterials and chip-based nanostructures for capillary electrophoretic separations of DNA.

Capillary electrophoresis (CE) and microchip capillary electrophoresis (MCE) using polymer solutions are two of the most powerful techniques for the analysis of DNA. Problems, such as the difficulty of filling polymer solution to small separation channels, recovering DNA, and narrow separation size ranges, have put a pressure on developing new techniques for DNA analysis. In this review, we dea...

Capillary electrophoretic separation of nanoparticles

In the present work, CdSe nanocrystals (NCs) synthesized with a trioctylphosphine surface passivation layer were modified using amphiphilic molecules to form a surface bilayer capable of providing stable NCs aqueous solutions. Such modified nanocrystals were used as a test solute in order to analyze new electrophoretic phenomena, by applying a micellar plug as a separation tool for discriminati...

Chiral Separations in Capillary Electrophoresis

We carried out different research projects by using our expertise in the field of the study of equilibria in solution, the synthesis and the NMR characterisation of cyclodextrin derivatives, capillary electrophoresis techniques, and electrospray mass spectrometry for the detection and the characterisation of the involved analytes. The most of our work concerns the separation science, and partic...

Ultra-fast DNA separations using capillary electrophoresis.